Antibacterial activity and mechanism of action of zinc oxide. In several studies the antimicrobial effect of zinc oxide coatings against different bacteri a can be already verified 2023. Earlier studies have shown the potential of zno nps in stimulation of seed germination and plant growth as well as disease suppression and plant protection by its antimicrobial activity. Original article antibacterial activities of zinc oxide. Asamoah, abu yaya, bismark mensah, pascal nbelayim, vitus apalangya, yaw d. This study aimed to determine the antibacterial activity of either zinc oxide or copper oxide nanoparticles alone or combined against grampositive and gramnegative. Antibacterial activity of zinc oxide nanoparticles znonps has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region. Antimicrobial activity of cerium oxide nanoparticles on.
Pdf antibacterial activity of zinc oxide nanoparticles. Pdf antimicrobial activity of zno nanoparticles against. Incorporated zinc oxide graphene oxide and its antibacterial. The true particle sizes of nps in medium were significantly larger than the advertised sizes. Zinc oxide nano particles are better antibacterial agent 2122. All english, spanish, and portuguese articles related to the topic that were published. Whitelightactivated antibacterial surfaces generated by. Among the drug resistant strain, management of methicillin resistant staphylococcus aureus mrsa is very difficult by using conventional antibiotic treatment. Zinc oxide nanoparticles znonps were synthesized by the solgel method at various ph values.
This study evaluated the antibacterial activity of zinc oxide nanoparticles incorporated into self. Therefore, introducing a fast and inexpensive method for synthesis with production on. The antimicrobial activity of zno nps has not studied on the carbapenem resistant strain of a. Bovine mastitis causes severe economic loss to the dairy industry 1 and poses considerable risks to. Thus, zno in nanoscale has shown antimicrobial properties. Particle size concentration of zinc oxide nanoparticles antibacterial activity by agar well diffusion method. Zinc oxide nanoparticles zno nps are considered as a biosafe material for biological species. The antibacterial activity of nanosized metal compounds has also been confirmed in both grampositive staphylococcus aureus and bacillus subtilis and gramnegative bacteria escherichia. Antibacterial activity of zinc oxide and ag doped zinc oxide. Pdf antimicrobial growth inhibition and mechanistic activities of synthesized zinc oxide nanoparticles zno nps were investigated in this study find, read. For the development of antibacterial textiles for applications on a large scale, e. Zno nanoparticles against pathogenic bacteria and fungi. In this study, we evaluated the antiviral activity of zinc oxide nanoparticles znonps and pegylated zinc oxide nanoparticles against h1n1 influenza virus. Antibacterial activity of zinc oxidenanoparticles znonps has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region.
Antibacterial activity of zinc oxide nanoparticles against. In vitro antibacterial activity and minimum inhibitory. For the retrieval and selection of articles, the following keywords were used. Biosynthesis of zinc oxide nanoparticles using aspergillus fumigatus jcf and its antibacterial activity international journal of modern science and technology 2. Antimicrobial activity of titanium dioxide and zinc oxide. Stock cultures were prepared by inoculating the strains in tryptone soya agar tsa himedia, india, followed by. In the composites, zno nanoparticles nps, with a size of about 4. During drying, complete conversion of zinc hydroxide into zinc oxide takes place. Both zinc oxide nanoparticles znonps and pancreatin pk are known to have antibacterial activity. Xrd, ftir, fesem, uvvis and pl were accomplished to characterize the structural, functional groups, morphology, and optical properties of the samples. Nanoparticles can be useful for preventing the distribution of resistant bacteria in the hospital and community. Green synthesis, characterization and antibacterial.
Here we get a new line of high purity zinc oxide nanoparticles primarily targeted for antimicrobial activity against bacillus subtilis and escherichia coli. Zinc oxide zno nanoparticles have received a remarkable consideration due to their extra ordinary uv filtering properties, photochemical antifungal, high catalytic and antibacterial activities. The gics, fuji ii gc america and fuji ii lc gc america, were incorporated with nanoparticles at concentrations of 0%, 1%, and 2% by weight, and the biofilm maturation time was one and. The effects of particle size and concentration on the antibacterial activity of zno nanoparticles was studied using bacteriological tests such as disc and well diffusion agar methods, minimum inhibitory concentration mic and minimum bactericidal concentration mbc. Enhanced antibacterial activity of capped zinc oxide. Its prevalence increases gradually in the clinical setup. Superior antibacterial activity of zinc oxidegraphene. Zno is currently listed as a generally recognized as safe gras material by the food and drug administration and is used as food additive. In the present study the antibacterial activity of zinc oxide zno nanoparticles was investigated against gram negative escherichia. Zinc oxide zno is a provocative material for applications in electronics, photonics, acoustics and sensing. Mar, 2014 formation of biofilms is the main contributing factor to antibiotic resistance. Oct 15, 2011 the antibacterial activities of magnesium oxide nanoparticles mgo np alone or in combination with other antimicrobials nisin and zno np against escherichia coli o157. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. Recently, the green synthesis of zinc oxide nanoparticles have been a keen interest amongst researchers and scientist.
Antibacterial activity of zno nanoparticle suspensions on a. Green synthesis of zinc oxide nanoparticles znonps using. Antibacterial activity of zno nanoparticle suspensions on. The antibacterial activity of znonps was tested against grampositive bacteria, bacillus cereus atcc 11778 and staphylococcus aureus atcc 25923, and gramnegative bacteria, pseudomonas aeruginosa atcc 27853 and salmonella typhimurium atcc 1428. Antibacterial activity and biocompatibility of threedimensional nanostructured porous granules of hydroxyapatite and zinc oxide nanoparticlesan in vitro and in vivo study l grenho1,2,3,6, c l salgado1,2,3,6, m h fernandes4, f j monteiro1,2,3 and m p ferraz5. In vitro antibacterial activity of zno and nd doped zno nanoparticles against esbl producing escherichia coli.
Influence of ph variations on zinc oxide nanoparticles and. Nanoparticles zinc oxide antibacterial antifungal reactive oxygen species. Dual uv irradiationbased metal oxide nanoparticles for enhanced antimicrobial activity in escherichia coli and m bacteriophage. Feb 04, 2011 the antibacterial effect of zinc oxide zno nanoparticles on campylobacter jejuni was investigated for inhibition and inactivation of cell growth. Antibacterial activity of glass ionomer cement modified by. Biosynthesis, characterization, and antibacterial activity of. Parkin, materials chemistry research centre, department of chemistry, university college london, 20 gordon street, london wc1h. However, chemical methods are more suitable for industrial scale production 35 due to its low efficiency and. Inhibition of h1n1 influenza virus infection by zinc oxide. Antibacterial zinc oxide nanoparticle coating of polyester. Antibacterial activity of zinc oxide nanoparticles on staphylococcus aureus. Therefore, we aimed in this study to test the antibacterial activity of zno nanoparticles on important and perilous bacteria such as. Zinc oxide zno is an inorganic compound widely used in everyday applications.
However, synthesizing nanoparticles is complicated, and nano products create another serious problem in the environment. Determination of the antibacterial activity of metal oxide nanoparticles. Zinc oxide nanoparticles prepared from the solution of zinc acetate, peg and ammonium carbonate. Therefore, we aimed in this study to test the antibacterial activity of zno nanoparticles on important and perilous bacteria such as p. Green synthesis of zinc oxide nanoparticles znonps. Pdf characterization and antibacterial activity of zno. Antibacterial activity of silver and zinc nanoparticles. Apr 19, 2015 antibacterial activity of zinc oxide nanoparticles znonps has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region.
Antibacterial activity comparison of three metal oxide. Damoah, benjamin agyeituffour, david dodooarhin and ebenezer annan publication date 22 jan 2020. Staphylococcus aureus are known to cause diseases from normal skin wound to life intimidating infections. The antibacterial activity against li was investigated under photocatalytic light setup equipped with 250watts halogen lamp. Zno nanoparticles can be obtained by physical and chemical routes. Antibacterial activity of trimetal cuznfe oxide nanoparticles khalid e alzahrani,1,2 abdurahman a niazy,3 abdullah m alswieleh,4 rizwan wahab,5 ahmed m eltoni,2 hamdan s alghamdi3 1department of physics and astronomy, king saud university, riyadh, kingdom of saudi arabia.
Antibacterial activity of silver and zinc nanoparticles against vibrio cholerae and enterotoxic escherichia coli author links open overlay panel wesam salem a b deborah r. Antibacterial, antibiofilm activity and mechanism of. Acinetobacter baumannii is a multidrug resistant opportunistic pathogen, which causes respiratory and urinary tract infections. Pdf this study was aimed to synthesize zinc oxide nanoparticles from the aqueous peel extract of aloe vera and assess their antimicrobial. Pdf antibacterial activity of zinc oxide nanoparticles on. Znonps exhibit attractive antibacterial properties due to increased specific surface area. Antibacterial activity and biocompatibility of three. Whitelightactivated antibacterial surfaces generated by synergy between zinc oxide nanoparticles and crystal violet ekrem ozkan, elaine allan, and ivan p. Antibacterial activity and mechanism of action of zinc oxide nanoparticles against campylobacter jejuni yanping xie, 1yiping he, 2 peter l. Ultrasensitive silverbasedcolour staining of polypeptides in polyacrylamide gels. Antibacterial activity preparation of nanosuspension synthesized nanoparticles was suspended in 1 ml of dilute sodium hydroxide solution 0. Currently, different types of engineered nanoparticles are used in polymer matrices and for the enhancement of mechanical, thermal, optical, gas barrier, and antibacterial properties. Recently, the green synthesis of zinc oxide nanoparticles have been a. The advent of nanotechnology has led the development of materials with new properties for use as antimicrobial agents.
Zinc oxide nanoparticles znonps have been reported as an antimicrobial agent against both pathogenic and spoilage microorganisms ann et al. Antimicrobial activity of zno nanoparticles against. Taking advantage of zinc oxide zno and graphene oxide go, the znogo composites were prepared by a facile onepot reaction to achieve superior antibacterial properties without damaging other species. However, there are several methods to produce the nanoparticle, hence. But the ag doped zinc oxide nanoparticles showed better antibacterial activity than the zno nanoparticles. In this study, the antimicrobial activity of titanium dioxide tio2, zinc oxide zno, and tio2zno nanoparticles supported into 4a zeolite 4a z was. Antibacterial activity of zinc oxide nanoparticles on staphylococcus aureus seyedeh atefe aleaghil 1,3, esmail fattahy 2, basireh baei 1,3, mansour saghali 3, hanieh bagheri 3, naeme javid 3. Antibacterial activity of synthesized zinc oxide nanoparticles 43 the species in the philippines. Both nanozinc oxide and bulk zinc oxide are 4080fold less toxic than znso 4 against v. Optical, thermal, and structural properties of polyurethane. Antibacterial effects of zinc oxide nanoparticles zno np on escherichia coli o157. Apr, 2016 in vitro antibacterial activity of zno and nd doped zno nanoparticles against esbl producing escherichia coli. New materials with good antibacterial activity and less toxicity to other species attract numerous research interest. Biosynthesis, characterization, and antibacterial activity of zinc oxide nanoparticles derived from bauhinia tomentosa leaf extract g.
Original article antibacterial activities of zinc oxide nanoparticles against escherichia coli o157. Antibacterial activity and mechanism of action of zinc. Antibacterial activity of zinc oxide nanoparticles on staphylococcus aureus article pdf available april 2016 with 2,342 reads how we measure reads. In vitro antibacterial activity of zno and nd doped zno. Antibacterial activity of zinc oxide nanoparticles synthesized by solochemical process brailian journal of chemical ngineering, ol. The present study of antibacterial activity of zno npi and zno npii against staphylococcus aureus suggest that both zno npi and zno npii have a little retarded antibacterial effect against s. This study was carried out to determine the antimicrobial activity of zinc oxide zno nanoparticle against isolated staphylococcus aureus. Nov 25, 2019 in this study, the antimicrobial activity of titanium dioxide tio2, zinc oxide zno, and tio2zno nanoparticles supported into 4a zeolite 4a z was assessed. Data are shown with mean values and standard errors of bacterial counts. Antibacterial activity of zinc oxide nanoparticles against toxigenic bacillus cereus and staphylococcus aureus isolated from some egyptian food azza a. Antibacterial activities of zinc oxide nanoparticles. The antibacterial effect of zinc oxide zno nanoparticles on campylobacter jejuni was investigated for inhibition and inactivation of cell growth. To identify the agents with potential antibacterial effects, six metal oxide nanoparticles mgo, tio 2, al 2 o 3, cuo, ceo 2 and zno were selected for our preliminary studies in liquid broth culture with aeration. When the size is 12 nm, it inhibits the growth of s.
The development of reliable processes for the synthesis of zinc oxide nanoparticles is an important aspect of nanotechnology today. Pdf antibacterial activity of zno nanoparticle on gram. Ewa karwowska antibacterial potential of nanocomposite. Antibacterial activity of synthesized zno nanoparticles against s. The results show that the zno nanoparticles have bacteriostatic activity against e. Zinc oxide nanoparticles zno nps are a multifaceted ntype semiconductor material with a wide band gap 3. In vitro evaluation of antibacterial properties of zinc oxide. Biosynthesis, characterization, and antibacterial activity. Green synthesis and characterization of zinc oxide. Initial cell concentration was around 109 cfu ml1, and aqueous znonps suspensions ranged. One of the main health problems is increasing resistance of bacteria to antimicrobial agents worldwide.
Antibacterial activity of modified zinc oxide nanoparticles. Mechanism of antibacterial activity of zinc oxide nanoparticle. Pdf the aim of the present study is to determine the antimicrobial activity of zno nanoparticles against gramnegative and grampositive bacteria find. Unexpected insights into antibacterial activity of zinc. Synthesis,characterization and antibacterial properties of zinc oxide nanoparticles 47 particle size, morphology and structure 3537. The results show that mgo np have strong bactericidal activity against the pathogens, achieving more than 7 log reductions in bacterial counts. In order to investigate new effective and inexpensive therapeutic approaches, we analyzed nanoparticles synthesized by a green approach using corresponding salt silver or zinc nitrate with aqueous. Photocatalytic antibacterial application of zinc oxide. Pdf antibacterial activity of zno nanoparticle on grampositive.
Pdf antimicrobial activity of zinc oxide nanoparticles synthesized. The nanoparticles were characterized using the inductively coupled plasma mass spectrometry, xray. Antibacterial activity of zinc oxide and ag doped zinc. Znonps exhibit attractive antibacterial properties due to increased specific surface area as the reduced particle size leading to enhanced particle surface. Zingl a 1 gebhart schratter c ruth prassl c walter goessler d joachim reidl a stefan schild a. Antimicrobial activity of zinc and titanium dioxide. Vibrio cholerae and enterotoxic escherichia coli etec remain two dominant bacterial causes of severe secretory diarrhea and still a significant cause of death, especially in developing countries. Synthesis and characterization of zinc and copper oxide. Green synthesized zinc oxide nanoparticles exhibit multifunctional behaviors and dynamic antibacterial activity 24. However, chemical methods are more suitable for industrial scale.
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